Pierre Garcon, Peyton Manning, and Reggie Wayne watch from the Colts sidelines against the Chiefs. (Brent Smith | Reuters)

Keys to winning the game:

*Keep the Cowboys running game in check: Although they are without Barber they still have two capable backs, and the Colts are not exactly known for their run defense.

* Offensive Line: The Colts line must give Manning more time than they did against San Diego or we are in for a very long day.

*Wide Receivers: They need to improve their timing and reduce their drops. Look for Wayne to make up for his issues last week.